

Yes.
First, yes, WordPress can be federated with a plugin.
If you’re looking for the easiest, most developed, option, it’s usually WordPress.
Alternately, there are many ways to join anything that produces RSS to the Fediverse.
(And of course WordPress also supports RSS)
(And lots of other hosted options support RSS!)
Static site generators like Jekyl and 11ty are particularly well suited to building a website to share comics.
Both can also produce an RSS feed, with the correct plugin.
An RSS file is a plain text, computer readable file that you add to your website, containing a list of all recent posts that you want to promote.
Anytime I add a post to my blog, I update my RSS file. (Well, a piece of automation does, I could hand edit it, but I’m lla lazy programmer.) Then a service I registered with shares any new posts (posts with today’s date) to services line Mastodon or Lemmy through bot accounts that I set up.
People can also subscribe directly to the RSS feed (file), using various news reading apps. (But I think following RSS through Mastodon and Lemmy bots is becoming more popular, lately?)
You can learn a lot more about the RSS through the RSS Specification, but you may not need to.
I find that WordPress and other blog solutions mostly just make good default assumptions whenever I have turned on the RSS feature or plugin.