• 2 Posts
  • 43 Comments
Joined 3 months ago
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Cake day: March 14th, 2025

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  • This is really interesting. As I was reading the article I was wondering how they were going to wring money out of it, as amlodipine is off patent. Then I got to this part:

    “While amlodipine shows promise in preclinical models, it is not currently suitable for use in ADHD in its marketed form,” Karlsson noted. “Further optimization through chemical modification is necessary to enhance CNS selectivity and ensure a favorable therapeutic index in the context of ADHD.”

    Classic big pharma. Slightly tweak an existing drug in an insignificant way so that you can get a new patent on it and charge exorbitant prices.



  • I’m with you. I’ve been a redditor for more than a decade, and I’ve really been disappointed with it’s decline. It’s gotten much worse lately. Not only is reddit clamping down on speech, more people there are just assholes now. Yesterday I made a comment on a thread about cops chasing a graduate that had brought a baby on stage. In response to a comment about the cops handcuffing the baby, I suggested that they would probably punch the baby in the face while yelling “stop resisting!” Obviously a joke and clearly not advocating violence, but my comment was deleted and my entire reddit account was suspended for 3 days. Jokes on them, as I’m not interested in going back.

    Edit:

    I didn’t word this well. Someone made a joke something like “what were they going to do when they catch her, handcuff the baby?” No babies were actually harmed.