• Approximately 75% of breast cancers are of a certain type.
• We know of ways to target this type of cancer directly and indirectly.
• However, these methods rarely fully cure the problem, and the patient eventually develops a resistance to these treatments, which makes continued use less effective.
• We recently examined and reported on a drug which targets this common cancer type in a novel way and is remarkably effective.
• However, that drug also interacts with non-cancerous cells in certain contexts, which ideally you want a cancer-targeting drug to avoid wherever possible.
• We examine and report on a variant of this drug that is similarly effective but is less likely to target non-cancerous cells.
• It is tolerated well in rodents, and this drug and related drugs are worth exploring for treating this cancer type.

This information has been laundered through two different websites, and ultimately the journal article can be found here so you don’t have to play a game of telephone written by someone who has literally no qualifications to do so.

Issue requests or pull requests?

How dare you!! Here’s why you need to be vegan right now by the way grumble grumble grumble

My point being I see no reason why Kickstarter can’t be for kickstarting the rapid scaling of a free, available-to-all project when it can be for rampant, unadulterated scams. This is easily within the spirit if not the letter of Kickstarter, unlike the scams which fit the letter but not the spirit.

That’s my point: Kickstarter and IndieGoGo is filled with extraordinarily obvious scams, yet this person’s trying to act like there’a some sanctity to the semantics rather than the spirit of them.

Yeah, no, not at all. I’d feel intensely uncomfortable using Sup for anything when something like Signal exists. The network effect issue is the exact same on both platforms, so why am I going to take the most trusted communication application and protocol in the world and choose Sup which is the work of a single dev with no obvious background in cybersec, let alone the kind of math necessary to properly understand encryption?

Oh no, someone is tarnishing the sacred name of a kickstarter campaign by checks notes raising money to scale up a project that can benefit everyone (thus kickstarting the scaling effort) instead of selling a $250 plastic brick that generates far-infrared waves using no electricity in order to “stabilise” your car’s battery which you velcro the brick on top of (okay, that one was an IndieGoGo, but same difference).

Wikipedia editor here; there’s some nuance. This article is listed as a Good Article, meaning it’s been reviewed by another (almost certainly) experienced editor for verifiability, prose and style, coverage, neutrality, stability, etc. This was attained in 2013, and especially for such a prominent article, slipping below those standards is a recipe to get GA status revoked. Presumably this note is summarizing a large portion of coverage by Wikipedia and thus a variety of sources. You want to read and cite all of the sources rather than Wikipedia in something like a research paper, but for just a community note, there’s really nothing wrong with this.

Word of mouth provided by pirates is still great for the AAA games industry, regardless of what they’ll tell you, and only helps perpetuate these bad practices you’re pirating to get away from. 99.9% of users are unwilling to pirate games, and thus when you reference them, say you played or enjoyed them, talk about pirating them, etc., it’s essentially just free advertising for those games to people who would in all likelihood just purchase them if they wanted them.

Meanwhile, playing indie games gives those devs some cash flow to keep developing and gives free, word of mouth advertising to other people through references, recommendations, etc. The more successful indie games with good practices are, the better the games industry as a whole. It’s not a zero-sum game, but there is some tradeoff involved.

Why pirate shitty AAA games when you can spend your time getting a better experience by supporting indie devs financially and in word of mouth?

“Here’s my angry, unpopular, barely coherent diatribe apropos of nothing about this large and diverse group of people definitely being angry and hostile.”

There isn’t a meaningful difference; gachas are just a subset of lootboxes, and anybody claiming otherwise is a player lying to themselves or is a game publisher defending themselves from these predatory practices.

I wish they would put the official app on F-Droid. I use PixelDroid, but it’d still be nice to try.

Flat Earth is exactly tantamount to claiming that ADHD doesn’t exist or that climate change isn’t real – in fact, it’s actively far less rooted in reality than either of those two already incredibly dumb takes.

By this logic, anyone on /c/ADHD has to debunk someone dropping in every once in a while (because it can’t be persistent, but the admins won’t define what persistence is) and saying that ADHD isn’t a real thing. Or /c/climate has to listen to speeches about how the Earth isn’t really warming and this is just like that “fake” ozone scare! (Nah, wait, that’s solarpunk whose administration is actually sensible in this respect.) Or we at /c/vegan have to attentatively listen and refute people coming in and saying that needlessly murdering animals is super cool and good actually (a very healthy thing for a vegan community). All relevant; all asinine.

You mean like LW ToS 8.0 against misinformation? So interesting that as soon as the head admin steps down, this ridiculous bullshit crops up. Sounds like he was holding back the floodgates from the other admins’ worst impulses, like the one a few months ago who briefly overtook an entire community because what they were saying agreed with science but hurt his fee-fees.

In a time of crisis where 75% of US adults are overweight or obese, it actually is a good thing that we talk to people in our lives about things we’re doing to lose weight, as long as that’s being used as a positive example and not a way to act superior. (Also, if eating salads makes you sad, you’re doing salad wrong; iceberg lettuce with a few croutons and dressing is a salad in the same way that unseasoned broth with noodles and nothing else is soup.)

Nah, monopolies like Luxottica can suck shit (although there are plenty of brands not owned by them that you can just as easily buy). Doesn’t change that 3D-printed anything is made of cheap, relatively brittle material compared to easily affordable monel, titanium, and other metal frames. I can’t speak to the durability of plastics manufacturers use versus what you would use DIY, but the metals have to be much more durable, and they consistently look much nicer than the 3D-printed ones I’m seeing online. Also, unless OP’s are somehow way above the ones I’m seeing online in terms of quality, they’re probably more comfortable as well; you can cope all you want that you painstakingly designed it to the contours of your face as much as I can cope that the t-shirt I weaved out of corn husks is better than that mass-produced crap because I tailored it to the contours of my torso.

It’s cool, don’t get me wrong, but this seems like one of the last ways I would try to cut corners financially.

Also, given I wear these almost every waking hour of my life and I’ll be shit-out-of-luck if these break while I’m out and about, they’re one of the last things I’d want to cheap out this badly on. Assuming you aren’t getting high-end designer frames, you’ve saved $40–$60 at the cost of spending the next two years wearing a dinky piece of brittle, probably uncomfortable plastic on your face. Yay…?