X lost half a billion dollars in the first quarter of 2023. Odd that the financial expert didn’t mention this even though it is literally in the same sentence as the “40% drop in revenue” statement in the article.

Lots of stretching here. The paper uses simulations of microtubules to show quantum effects when tryptophan residues are excited by UV light. The paper only did simulations of microtubules, and those simulations did not include the bends and many many dynein molecules found on microtubules. The reason this is important is that researchers have been hitting every biomolecule with UV excitation for decades, including microtubules, and have never observed this effect.

A key finding missing from this video is that microtubules are dynamic. They are constantly disassembling and reassembling and recycling components. This occurs at very short timescales. Also, they do not bridge cell membranes. If information is passing through networks of microtubules, it is constantly disrupted and not affecting other cells. Synapses do handle cell-cell information transfer (where the role of microtubules is already well studied and not quantum in nature). Why would quantum microtubule information be limited to a single cell? Maybe it could influence coordinated assembly and disassembly at the termini, but the authors offer no evidence that there is any chemical effect of this quantum phenomenon, which would be required to change anything about how those enzymes behave.

We already know of a mechanism by which information is transported across microtubules: physical transport of signalling molecules. They are walked (quite literally, dynein is cool) along the microtubules to different sites in the cell. No quantum effects needed to explain this phenomenon.

They sell CBD oil with this little droppers for dosing, but when you read the studies the dosage is like a mouthful of oil. It’s like the exact opposite problem of melatonin dosing.

My shower thoughts are always repeating cycles of “fuuuuuuuck this feels niiiiiiiiice” and “time to turn up the heat a smidge.” Am I doing it wrong?

For real, we’ve got the first openly pro-union president, we expanded NATO, student loan forgiveness, actual infrastructure funding, the first administration to openly push back against Israel during war time, all of that in only 4 years. He is the most effective president of my lifetime and I am happy to vote for him again.

A similar thing happens with cockroaches where crucial bacteria are absorbed into cells to ensure inheritance in offspring.

Avoiding advertising is the best way to avoid influence, but remember that pretty much everyone wants you to change your mind ina way that benefits them. Avoiding influence altogether is impossible, and that influence is necessary to stay informed and make good life choices.

My advice is twofold. First, learn the logical fallacies and how to identify them. Second, account for uncertainty in your decisions. The most practical application of this second point is to favor decisions that leave you with more options in the future. This uncertainty should include you. Account for the possibility that your goals and views may change in the future, because they will.

I would never allow my DNA to be characterized or sequenced outside of a medical setting where strict privacy laws are in place.

The real problem with government housing in the US specifically stems from our worship of billionaires, which requires us to demonize the poor. If a rich man is selfmade due to his virtues then poor people must lack virtue. That worldview implies that no amount of help will redeem the poor. Thus safety net programs are half-assed at best, and cut to bare bones or cut entirely at the worst.

The narrative that government-run programs are useless just does not hold up to the evidence. Even the housing program you mentioned is an improvement over nothing. But take a look at some of our programs and imagine the horror of a private alternative: US Postal service (I can send a letter to the smallest town in Alaska with a single stamp), rural electricity, roads (my God could you imagine a private road system), public school. You need to remember that the alternative to any flawed government program is NOTHING.

I have obviously simplified the role of dopamine in the brain to make it more digestible, but you are dead wrong about dopamine’s role in intermittent reward and the link to gambling addiction. It has a very strong influence on behavior. Like many aspects of human behavior, the effect is not an on-off switch to enable gambling addiction. We have lots of things going on in our head that are, at times, working against each other as far as behavior is concerned. It is more like an analog adjustment that “pushes” toward a specific behavior much harder than it otherwise would. And this effect is just as powerful as addictive chemicals in potency.

This is a pretty complicated topic that touches video games, gambling sites, social media algorithms, and marketing in general. It also touches fundamental philosophical questions like the existence of free will.

We have lots of established law on which sort of “mind tricks” are fair play and which aren’t, but we have not advanced those laws to keep pace with the science. Currently, lying is really the only thing off limits and is covered by fraud statutes. We also have some limits on marketing to children. But one could argue that there are several “persuasion” tactics that can be just as effective as outright lies in manipulating the behavior of others. In fact, licensed therapists are ethically barred from using these tactics, yet we allow salesmen, marketers, etc to use them at will.

I don’t really have an opinion on this lawsuit, nor do I feel qualified to offer a solution. But let me give you an example of how the human mind works which underpins addiction to gambling.

Dopamine is a signaling molecule that regulates a lot of our reward responses. If I find honey in a honeycomb, dopamine gets released and now I am more likely to seek out honeycombs in the future. You can see how this is evolutionarily beneficial. Dopamine release reinforces behavior that increases survival. But let’s say that only about 1/3 of all honeycombs have honey. Now I have a lower chance at a reward, so does that mean the dopamine release is likewise diminished? No, the opposite is true. Dopamine release skyrockets. Evolutionarily this makes sense, we do not want to miss out on a reward simply because the probability is diminished, so the high dopamine release counterbalances the diminished probability such that reward seeking behavior is reinforced so long as the probability of reward is reasonable (it peaks at about 1/4). In fact, dopamine is released even when the honeycomb has no honey. You can draw a direct line between this physical phenomenon and gambling addiction. What people don’t appreciate is that this physiological response is very similar to addictive drugs in effectiveness. It can be hard to acknowledge that one of the reasons you are not a gambling addict is simply that you didn’t start gambling to begin with, not that you are somehow superior to those that are addicted.

We have lots of behavioral quirks like this that can be exploited. At what point does this manipulation cross the line? That is a hard question. For me, gacha games cross that line. But if we want to enact meaningful regulations we need to acknowledge that these mind exploits exist and confront the fact that free will may not be as free as we hope.