I brush my teeth in bed and swallow the toothpaste at the end. According to the chemical fact sheet swallowing my toothpaste is well within osha defined limits for sodium flouride, and people who live in places with naturally more fluoridated water than where I am are exposed for far more than I am. so I really don’t think there is any health concern. I have been doing it for a decade now and I have no symptoms of over exposure. I find it greatly helps me fall asleep if I don’t have to get out of bed to brush.